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Фотографии выпусков прошлых лет.
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| sisadmin | Дата: Пятница, 18 Сентября 2009, 16:18 | Сообщение # 1 |
 Одинадцатиклассник
Группа: Администраторы
Сообщений: 3
Статус: Offline
|  Уважаемые гости, посетители и пользователи сайта!
Создавая свой школьный сайт, мы решили расширить наш фотоальбом и включить в него фотографии выпусков нашей Санкинской школы. Но мы столкнулись с проблемой отсутствия материалов (т.е. фотографий).
И поэтому мы обращаемся за помощью к вам. Уважаемые посетители, если вы учились в нашей школе и у вас есть фотографии с вашим выпуском - пожалуйста, пришлите на электронный почтовый ящик sankinoschool@mail.ru в электронном варианте фотографию выпуска с указанием года, и, по возможности, фамилии выпускников и учителей.
Мы будем вам очень признательны!!!
С уважением
Администрация Сайта sankinoschool.ucoz.ru .
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| tcsindustryv | Дата: Среда, 04 Марта 2015, 15:03 | Сообщение # 196 |
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Группа: Гости
| Docetaxel (as generic or underneath the shoppers specify Taxotere) is a clinically set anti-mitotic chemotherapy medication (medication which interferes with stall division). It is used in general to the treatment of heart, ovarian, prostate, and non-small room lung cancer.<> - <> - <> - Docetaxel has an FDA approved claim representing treatment of patients who arrange locally advanced, or metastatic mamma or non small-cell lung cancer who suffer with undergone anthracycline-based chemotherapy and failed to put an end cancer chain or relapsed<> - and a European rubber stamp instead of exploit in hormone-refractory prostate cancer.<> -
According to a 2005 article in the magazine Drugs, docetaxel administered as a one-hour infusion every three weeks commonly as surplus a ten rotate dispatch, docetaxel is considered as or more real than doxorubicin, paclitaxel and fluorouracil as a cytotoxic agent.<> - Respect the effectiveness of docetaxel versus paclitaxel and other taxanes is quiescent controversial. Individual more current articles have found "no sign that regimens containing docetaxel yield greater benefits than those including paclitaxel."<> - Additionally, the optimal scheduling of docetaxel and other taxanes remains unconfirmed. A three-week dispensation register hardened to be and is stationary considered operative but new studies are indicating a weekly plan might be better. A 2010 article in Prevailing Clinical Pharmacology states, "weekly application has emerged as the optimal schedule." Docetaxel is marketed worldwide under the honour Taxotere nearby Sanofi-Aventis.<> - Annual sales in 2010 were Euro 2.122 billion ($US 3.1 billion). The transparent expired in 2010.<citation>
Stamp
Docetaxel is of the chemotherapy knock out class; taxane, and is a semi-synthetic analogue of paclitaxel (Taxol), an quotation from the bark of the rare Pacific yew tree Taxus brevifolia.<> - Fitting to inadequateness of paclitaxel, vast delving was carried visible leading to the formulation of docetaxel – an esterified yield of 10-deacetyl baccatin III, which is extracted from the renewable and agreeably ready European yew tree.
Docetaxel differs from paclitaxel at two positions in its chemical structure. It has a hydroxyl functional dispose on carbon 10, whereas paclitaxel has an acetate ester, and a tert-butyl carbamate ester exists on the phenylpropionate side chain as a substitute for of the benzyl amide in paclitaxel. The carbon 10 functional group exchange causes docetaxel to be more sea water soluble than paclitaxel.<> -
Formulations and compositions
Docetaxel is a white coat capacity and is the strenuous ingredient available in 20 mg and 80 mg Taxotere single-dose vials of concentrated anhydrous docetaxel in polysorbate 80.<> - <> - The figuring out is a readable brown-yellow containing 40 mg docetaxel and 1040 mg polysorbate 80 per mL.<> - 20 mg Taxotere is distributed in a blister carton containing one single-dose vial of Taxotere (docetaxel) preparation in 0.5 mL sterile pyrogen-free anhydrous polysorbate 80, and a single amount Taxotere debt-free vial containing 1.5 mL 13% ethanol in saline to be combined and diluted in a 250 mL infusion shopping bag containing 0.9% sodium chloride or 5% glucose recompense administration.<> - 80 mg Taxotere is supplied identically but with 2.0 mL polysorbate 80 and 6.0 mL 13% ethanol in saline. The docetaxel and profitable vials are combined to bestow a colloidal suspension of 10 mg/mL and the required portion is haggard from this solution. Vials be suffering with an overfill to even up for solvent set-back during preparation, foaming, adhesion to vial walls and the numb volume. 20 mg vials may be stored looking for 24 months under 25 °C away from insight and 80 mg vials as far as something 26 months in the nevertheless conditions.<> -
Recently Sanofi has got approval in behalf of one-vial formulation.<citation>needed - With this one-vial formulation, the preparation of the infusion emulsion is simplified alongside eliminating the blue ribbon dilution step. The two-vial and one-vial formulations carry the at any rate panacea point, docetaxel trihydrate, and the but excipients (ethanol, polysorbate 80 and citric acid). The one-vial formulation is administered as an aqueous intravenous resolution that contains the despite the fact psychedelic substance in the after all is said concentration as the already approved two-vial formulation. The unvarying grade, quality, and measure of polysorbate 80 are proximate in the infusion explication of both formulations. The at best difference between these two formulations is the measure of ethanol.
From http://www.tcsindustry.com - TCS INDUSTRY LTD
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| fmyykjr | Дата: Среда, 08 Апреля 2015, 18:23 | Сообщение # 197 |
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Группа: Гости
| Milbemycin oxime is efficacious against a broad spectrum of nematodes, although it is less formidable against heartworms than ivermectin. Its miticide spectrum includes Sarcoptes and Demodex. The USA FDA mandate on milbemycin oxime as formulated alone does not call for insecticidal activity.<> -
The affluence is again combined with other parasiticides to accomplish a broader spectrum of action. Such products categorize:
Milbemax (with praziquantel)
Guard Flavor Tabs (with lufenuron)
Trifexis (with spinosad)
Recently the psychedelic has been acclimated to in nautical reef aquaria to control parasitic harptacoid copepod (Tegastidae) infestations on caged devastating coral colonies. It is an possessions saturated tank treatment for these parasites because it is not toxic to corals in the dosage required to idle the parasites. Shrimps, crabs and other crustaceans should be removed prior to treatment, as they disposition be killed via the treatment.
From http://www.tcsindustry.com - TCS INDUSTRY LTD
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| fmyykjp | Дата: Вторник, 14 Апреля 2015, 16:46 | Сообщение # 198 |
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Группа: Гости
| Varenicline (do business mention Chantix in the USA and Champix in Canada, Europe and other countries, marketed close to Pfizer, predominantly in the tone of varenicline tartrate), is a direction medication occupied to deal with nicotine addiction. Varenicline is a nicotinic receptor partial agonist—it stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar tocytisine and conflicting from the nicotinic contender, bupropion, and nicotine replacement therapies (NRTs) like nicotine patchesand nicotine gum. As a fragmentary agonist it both reduces cravings seeking and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms it can help some patients to discharged smoking.
Medical uses
Varenicline is indicated as a replacement for smoking cessation. In a 2006 randomized controlled trial sponsored next to Pfizer, after inseparable year the figure of continuous abstinence was 10% for placebo, 15% instead of bupropion and 23% for varenicline.<> - In a 2009 meta-analysis of 101 studies funded via Pfizer, varenicline was establish to be more effectual than bupropion (odds relationship 1.40) and NRTs (odds proportion 1.56).<> -
A Cochrane businesslike notice concluded that varenicline improved the strong of successfully quitting smoking by means of two- to three-fold conditioned by to pharmacologically unassisted attempts. Varenicline was more efficacious than bupropion in this view but not statistically upper to NRT.<> -
The FDA has approved the ingest of varenicline for up to twelve weeks. If smoking cessation has been achieved it may be continued in requital for another twelve weeks.<> -
Varenicline has not been tested in those directed 18 years close or productive women and thus is not recommended on abuse aside these groups.
Adverse effects
Nausea occurs commonly in people taking varenicline. Other less worn out side effects embrace cephalalgia, difficulty sleeping, and irregular dreams. Rare side effects reported sooner than people taking varenicline compared to placebo include change in discrimination, vomiting,abdominal woe, flatulence, and constipation. In a recent meta-analysis paper by Leung et al., it has been estimated that for every five subjects taking varenicline at conservation doses (1 mg twice routine), there will be an experience of nausea, and for every 24 and 35 treated subjects, there will-power be an event of constipation and flatulence respectively. Gastrointestinal side-effects are signal factors compromising the compliance of varenicline.<> - <> -
Depression and suicide
In November 2007, the FDA announced it had received post-marketing reports that patients using varenicline for smoking cessation had experienced not too life-and-death side-effects, including suicidal ideation and random suicidal behavior, haphazard behavior, and drowsiness. On February 1, 2008 the FDA issued an wide awake to then again shed its findings, noting that "it appears increasingly likely that there is an association between Chantix and acute neuropsychiatric symptoms". It is unknown whether the psychiatric symptoms are mutual to the medication or to nicotine withdrawal symptoms,<citation>needed - although not all patients had stopped smoking. The FDA also recommended that salubrity care professionals and patients ready for for behavioral and eager changes.<> - In May 2008, Pfizer updated the shelter news associated with varenicline, noting that "some patients have reported changes in behavior, agitation, depressed well-disposed, suicidal thoughts or actions."<> -
As of July 1, 2009, the US Edibles and Dose Administration requires Chantix (varenicline) to carry a moonless box tip, the agency's strongest security warning, precisely to viewable reports of side effects including depression, suicidal thoughts, and suicidal actions.<> -
From http://www.fmyykj.com - suzhou pharmaceutical technology co.,ltd.
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